what are the effects of thalassemia

You might also experience: Dizziness Shortness of breath A fast heart beat Headache Leg cramps Difficulty concentrating Pale skin. May 14,  · When there are not enough healthy red blood cells, there is also not enough oxygen delivered to all the other cells of the body, which may cause a person to feel tired, weak or short of breath. This is a condition called anemia. People with thalassemia may have mild or severe anemia. Severe anemia can damage organs and lead to death.

Since your body has fewer red blood cells when you have thalassemia, you may have symptoms of a low blood count, or anemia. When you have anemia, you might feel tired or weak. You might also experience:. Your body will try very hard to make more red blood cells. The main place where blood cells are made is the bone marrow, the dark spongy part in the middle of bones. Because your bone marrow may be working harder than normal, it might grow bigger.

This causes your bones to expand, and may stretch your bones and make them thinner and more easily broken. Another place where blood is made is an organ called the spleen. It sits on the left side of your abdomen, just under your lower ribs. The spleen has many other jobs. Two of the major ones are filtering the blood and monitoring the blood for certain infections.

When it finds these infections, it can start the process of fighting them. When you have thalassemia, the spleen can get very big as it tries to make blood cells. When you are immunocompromised, it is easier thalassemis you to get infections and you sometimes need extra protection, like flu shots and other vaccines.

The type of treatment a person receives depends on how severe the thalassemia is. The more severe the thalassemia, the less hemoglobin the body has, and the more severe what were napoleon bonaparte accomplishments anemia may be.

One way to treat anemia is to provide the body with more red blood cells to carry oxygen. This can be done through a blood transfusion, a safe, common procedure in which you receive blood through a small plastic tube inserted into one of your blood vessels. Some people sre thalassemia — usually with thalassemia major — need regular blood transfusions because their body makes such low amounts of hemoglobin.

People with thalassemia intermedia not as severe as major, but not as mild as trait may need blood transfusions sometimes, such as when they have an infection or an illness. People with thalassemia minor or trait usually do not need blood transfusions because they either do not have anemia or have only a mild anemia. Many times people with thalassemia are prescribed a supplemental B vitamin, known as folic acid, to help treat anemia.

Folic acid can help how do i connect my ipad to my ps3 blood cells develop. Treatment with folic acid is usually done in addition to other therapies. People who receive a lot of blood transfusions are at risk for iron overload.

Red blood cells contain a lot of iron, and over time, the iron from all of the transfusions can build up whta the body. When it builds up, the iron collects in places like the heart, liver, and brain, and can make it hard for these organs to work properly.

To prevent iron overload, people with thalassemia may need chelation therapy, which is when doctors give a medicine — either a pill or a shot under the skin — to remove excess iron before it builds up in the organs. Another concern for people who receive a lot of blood transfusions is the safety of the blood they hhalassemia.

Some infections, like hepatitis, can be carried in blood. In the United States, the blood supply is screened and monitored for safety, and the risk of getting an infection from a blood transfusion is very low. Nevertheless, there is still a very small risk of getting an infection through a blood transfusion. Learn more about complications of transfusions in thalassemia. Read more here about how CDC has been working with partners to better understand these health problems.

Skip directly to site content Skip directly to page options Skip directly to A-Z link. How to reference a website in bibliography Navigation. Facebook Twitter LinkedIn Syndicate. Thalassemia: Complications o Treatment. Minus Related Pages. If I have thalassemia, how does it affect my body? Hear Robert Mannino discuss how iron overload affects the body and why it is important to stay on track with thalassemia treatments.

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How is thalassemia treated?

Nov 13,  · Some of the most noticeable signs include: fatigue jaundice pale skin poor appetite slow growth. Jan 10,  · These include: jaundice and pale skin drowsiness and fatigue chest pain cold hands and feet shortness of breath leg cramps rapid heart beat poor feeding delayed growth headaches dizziness and faintness greater susceptibility to infectionsAuthor: Yvette Brazier. Mar 07,  · Thalassemia can take on myriad forms, and depending on what you're dealing with – alpha thalassemia or beta thalassemia, thalassemia trait, or thalassemia major – your symptoms may vary. Watch for signs like stunted growth, delayed puberty, pale or jaundiced appearance, fatigue, bone development issues, and dark colored urine.

Welcome, Guest. Please login or register. Advanced search. Tell everyone they can now find this site by typing this into their browser: thalpal. Battaglia Home Help Login Register. Forum Tip: Put your birthdate in your profile, under "Forum Profile Information," and it will automatically come up on our calendar. New Member Offline Posts: Does anyone know the long-term effects of minor? Now that I've entered middle age, and my dad from whom I inherited this disease is in his late 70s, I'm beginning to wonder what the long-term effects of this disease are.

Is it damaging my heart? Weakening my liver? Am I more susceptible to strokes or heart attacks than other "normal" people?

I haven't been able to find any information on this. There's only ever information on thal-major. When I asked my GP, he just told me that by my age, my body has "adjusted" to the disease and I should have little effects, if any. Re: Does anyone know the long-term effects of minor? Hi Kathy, Many thalassemia minors report no symptoms, but from the hundreds of minors who have joined this group, we also have to conclude that many minors do have symptoms.

The severity of the symptoms seems to be related to how low the long term hemoglobin level is. The long term effects of low hemoglobin and the resulting hypoxia low oxygen have never been studied, as most doctors and researchers have believed that there are no symptoms in thal minor.

I feel that this is a direct result of doctors not compiling the information given to them by patients, and also just outright rejection of the idea that any symptoms a person may have are related to being a minor. We know that this thinking is not valid because so many minors have come to this group with very similar stories and sets of symptoms.

With that said and based on these many posts and talks with minors and an understanding of what to expect in more serious thalassemia conditions, I will say what I suspect the long term effects of thal minor are.

First, thal minor does seem to have a positive effect on the heart in terms of protection against heart disease. This has been noted in studies, so not everything about it is a negative. However, long term oxygen deficiency can lead to pulmonary hypertension PHT or PAH which is high blood pressure in the artery between the heart and lungs. This is not related to your regular blood pressure. With the long term lack of oxygen comes a reduction in the amount of nitric oxide NO found in the artery and the heart.

This causes a loss of flexibility of the artery and a reduction in its effectiveness in moving blood to the heart. PHT is common in non-transfused thalassemia intermedias and I suspect that mild PHT is common in thal minors, but this has never been studied.

Even mild PHT can cause problems, so prevention should be a goal. The supplement, L-carnitine helps to fix NO in the body, so it is often recommended to thals and I think thal minors can also benefit from its use.

I would also highly recommend natural vitamin E. Many minors report problems that are related to poor circulation, and again this may be a result of mild PHT, as the veins and arteries lose flexibility, thereby impairing circulation. I don't think liver damage is a concern unless you have had long periods of iron overload, which can happen with long term iron supplementation and excess iron absorption from the diet, with the latter being related to Hb level. The lower the Hb, the more likely that excess iron absorption from diet will occur.

Andy All we are saying is give thals a chance. That is interesting. My dad, who is 76 years old and has thal minor, was recently told he has the heart of a 20 year-old man. Given his poor eating and exercise habits, we are all quite surprised at this, but what you are saying explains why. Thanks for the advice on nitrous oxide. I'll have to read up on that. Active Member Offline Posts: Long-term effect would be also vitamin exhaustion to the levels that low that it might be harmful.

Your demand for some vitamins is higher than recommended daily allowance, so in the long term you will finally get there - you will be deficient. What are the consequences of such deficiences often so-called sub-clinical, where I would define it as a deficiency that the body can deal with it, but it has to re-utilize and use the deficient compound very sparingly , it is still unknown, but rather not good. What are the consequences of being tired all the time as thals experience it?

Rather not good. I have for example blood iron out of normal range times out of range and what are the consequences of this? But on the bright side: if you know that thalassemia minor has symptoms, then it should be treated, and you will be able to avoid many of these pretty, pretty, pretty bad consequences.

Better yet - your health status will be better than this of normal person who does not care about health and may have deficiences for no good reason. Many "healthy" people have vitamin D, B12 deficiency, magnesium deficiency, microelements deficiency, etc.

Andy, I have often wondered if a long term affect of thalassemia minor can result in myocardial fibrillation. If so, I wonder if taking supplements can protect against this condition. Darn, I was just reading that L-carnitine can't be sold as a health product in Canada, and can't be imported. And I live in Canada. Any suggestions on what I should do to get this supplement, short of living on a diet of red meat? Quote from: kathysask on October 11, , PM.

Sharmin, I cant speculate on whether minors would be more likely to have a sudden, fatal heart event, but it seems far less likely than it does in major and intermedia. This will help regulate heart function. L-carntine plays an important role in maintaining NO levels, which helps maintain elasticity of the blood vessels, and should also be part of the program. Kathy, L-carntine has become a victim by association in some countries because bodybuilders use it along with steroids to build muscle mass.

It's a foolish policy that deprives people of an important nutrient that is already found in the body. If you can get it from the US, do so. Otherwise you must get a prescription and deal with the outrageous cost in Canada. Powered by SMF 1.

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4 thoughts on “What are the effects of thalassemia

  • Galrajas
    22.09.2020 in 23:44

    Daniel Schroedinger

  • Tojagor
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  • Marisar
    27.09.2020 in 10:44

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  • Kehn
    27.09.2020 in 12:58

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